In addition, Axl has been shown to mediate migration and invasion of glioblastoma, lung cancer and breast cancer cells by upregulating the expression of matrix metalloproteinases and promoting the transition of solid tumor cells from an epithelial to mesenchymal morphology [9, 35–38], and whether Mer functions by similar mechanisms in NSCLC remains to be investigated. The gene discussed is AXL; the disease is lung cancer.