HOXB13 expression was seen in 63.4% (ERG IHC) and 64.1% (ERG FISH) of ERG-positive cancers but in only 44.1% and 49.9% of cancers without ERG staining and ERG rearrangement, respectively (p < 0.0001 each; Figure 2). This evidence concerns the gene HOXB13 and cancer.