In fact, in METABRIC, BECN1 alone deletions were more common than BRCA1 deletions, indicating a further lack of confirmation of the findings of Laddha et al. In addition, Laddha et al. reported that there were no changes in the mean level of BECN1 mRNA expression in breast tumor samples versus normal tissue. The gene discussed is BRCA1; the disease is breast neoplasm.