In TCGA dataset (Supplementary Table 4), low BECN1 expression was associated with basal-like breast tumors (odds ratio 8.3 [95% CI 4.2 to 17.3], P = 3.8E− 12), HER2-enriched breast tumors (odds ratio 3.5 [95% CI 1.7 to 7.1], P = 1.7E− 04), and tumors with TP53 mutation (odds ratio 3 · 1 [95% CI 1.8 to 5.3], P = 1.0E− 05). This evidence concerns the gene TP53 and breast neoplasm.