These findings were corroborated by Nagatsuma et al. who reported a significant correlation between Japanese patients who had given birth most recently to higher rates of advanced stages of breast cancer, with an increased risk of negative estrogen and progesterone receptors and TNBC tumors when compared with nulliparous patients or those who had given birth less recently (Nagatsuma et al. 2013). The gene discussed is PGR; the disease is breast carcinoma.