CCAR2 and serous adenocarcinoma: When we did additional analysis in the subpopulation of serous carcinomas, the factors significantly associated with both OS and RFS by univariate analysis were the age of patients (OS; P = 0.002, RFS; P = 0.019), tumor stage (OS; P = 0.021, RFS; P = 0.001), histologic grade (OS; P = 0.041, RFS; P = 0.014), and DBC1 expression (Log-rank, OS; P < 0.001, RFS; P = 0.003), and BRCA1 expression (Log-rank, OS; P = 0.043, RFS; P = 0.034) (Table 2) (Figure 3).