CCAR2 and ovarian carcinoma: Expression of DBC1 was significantly associated with higher tumor stage (P = 0.015), bilateral tumors (P = 0.008), latent distant metastasis (P = 0.016), platinum-resistance (P = 0.016), higher pre-operative serum level of CA125 (P = 0.004), higher histologic grade (P < 0.001), histologic type of ovarian carcinoma (P < 0.001), and BRCA1 expression (P < 0.001).