The set of genes includes EXO1, knockdown of which has been reported to desensitize H196 lung cancer cells to paclitaxel treatment [24]; KIFC1, reported to modulate docetaxel sensitivity [25]; the breast cancer susceptibility gene CHEK2 [26, 27]; the Bloom syndrome gene BLM [28]; and the Survivin gene BIRC5, reported to associate with chemo- and radioresistance in breast cancer [29]. Here, BIRC5 is linked to Down syndrome.