Since there were no indications about the biologic significance of nNCoR loss in primary MM, we have here performed a high throughput transcriptome analysis of 4 MM samples with nNCoR and 3 MM samples that had lost nNCoR, but they all shared comparable histopathologic characteristics including the tumor stage (all stage II), the anatomic localization, and the distribution of BRAF, NRAS and Kit mutations (see Table 2). This evidence concerns the gene NRAS and neoplasm.