One such cancer, chronic myelogenous leukemia (CML), is associated with a characteristic translocation between chromosomes 9 and 22, called the “Philadelphia chromosome (Ph),” which encodes a fusion protein composed of breakpoint cluster region (BCR) protein and the PTK Abl1, called BCR-ABL[3]. The gene discussed is ABL1; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.