The Th1-type response plays a fundamental role in the protection against TB [2].Th1-type cytokines, such as IFN-γ and TNF-α, which synergize to activate the microbicidal mechanism of macrophages, and IL-2, which promotes the proliferation and maturation of T cells [33], are produced in the Th1-type response. This evidence concerns the gene IFNG and tuberculosis.