Several forms of post-translational regulation of Drp1 have been reported; it is possible that in oncocytic tumors, Drp1 could be stabilized, namely by Ser-616 phosphorylation or Ser-637 dephosphorylation, and translocated to mitochondria, thus promoting an unbalanced organelle division as previously described[45,46,47,48]. This evidence concerns the gene DNM1L and oncocytic neoplasm.