FOXP3 and Sepsis: In addition, the expression of Foxp3 in T cells cocultured with patient or control DCs suggested that CD1a+ DCs from septic patients made the T cells have a stronger regulatory function, because the percentage of naïve T cells expressing Foxp3 when cultured in patient DCs was much higher than that induced by control DCs (93% versus 40%) [61], which suggested that sepsis led to an increase in regulatory T cells (Tregs).