As shown in Table 2, the adipocyte-derived hormones adiponectin and visfatin were reciprocally altered by presence of components of MetS, such that visfatin levels were 3-fold higher in subjects in group MetS2 (P < 0.001), whereas adiponectin levels were 43% lower (P = 0.014). The gene discussed is ADIPOQ; the disease is metabolic syndrome.