Expressions of 11 genes were upregulated by diabetes: cxcl13, ccl5, il18, pf4, il13, abcf1, cxcr5, il10, c3, il16, and il15 (Figure 8(a)), and expressions of 31 genes were downregulated by diabetes: such as tnfrsf1a, casp1, ccr7, and cxcl10 (Figure 8(b)). Here, C3 is linked to diabetes mellitus.