This incidence is not statically different (P=0.15) from our previously published experiments where 38% (10/26) of mice injected with full length BRAFV600E and Cre viruses developed tumors; however, the mice with BRAF-FLVE-induced tumors had to be sacrificed before 12 weeks due to tumor burden [16] whereas the BRAF-KD mice demonstrated no obvious symptoms (Figure 3B). Here, BRAF is linked to neoplasm.