Analysis of the transcriptome has also been informative, in particular a recent study comprising 372 peripheral T cell lymphoma (PTCL) patients, including 31 ALCL ALK+ and 32 ALCL ALK− patient samples, that identified 29 genes that differentiated ALCL ALK+ from ALCL ALK−, although the overall molecular profile was similar between the two ALCL sub-entities [27]. The gene discussed is ALK; the disease is mature T-cell and NK-cell non-Hodgkin lymphoma.