Several genes have not been reported as candidate genes for complex diseases, including ACBD4, C10orf32, C15orf17, COX5A, FAM109A, ID1, MAPKAPK5, MPI, SCAMP2, and TRAFD1. Many of the detected genes have been reported to be associated with CAD, type 2 diabetes, hypertension, and stroke. The gene discussed is COX5A; the disease is hypertensive disorder.