For the tumor site (i) in Fig. 6(b), the distinct SERS bands in the Raman spectra were observed at 1285 and 1648 cm−1 corresponding to the anti-HER2-FAF610-SERSRITC dots, and at 1324 and 1633 cm−1 corresponding to the anti-EGFR-FAF610-SERSFITC dots. This evidence concerns the gene EGFR and neoplasm.