We also analysed the correlation between the area of synaptophysin in the CA3 sub-region of the hippocampus and the distance travelled to the platform in the MWM, which was significantly shorter in the CML-supplemented group than in the control group (p<0.05, n=16, Supplementary Fig. 1) (5). The gene discussed is SYP; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.