Regardless of initial weight loss attributed to diabetes induction and surgery until post-alloxan injection (PAI) 7, a trends towards weight gain was observed in the islet300/hESC-MSC:VEGF (28.6 ± 0.8 mg/day) mice compared to sham (p < 0.01, N = 7). The gene discussed is VEGFA; the disease is diabetes mellitus.