Whereas in these MITF‐negative cells, factors such as WNT5A and TGFβ appear to dominate the regulation of melanoma cell fate (Eichhoff et al., 2011; Javelaud et al., 2011), in the MITF‐positive cells, MITF is the central regulator of melanoma cell survival, proliferation and differentiation. Here, TGFB1 is linked to melanoma.