Although it is not entirely clear whether this downregulation is required for proliferation or just a consequence of ERK activation, forced overexpression of MITF in murine BRAF‐transformed melanocytes inhibits proliferation (Wellbrock and Marais, 2005), suggesting that the control of MITF expression levels by the MAPK pathway is important in BRAF‐driven melanoma growth. Here, MAPK1 is linked to melanoma.