For example, Dao expression and DAO activity are increased in schizophrenia (Kapoor et al., 2006; Verrall et al., 2007; Burnet et al., 2008; Madeira et al., 2008; Habl et al., 2009; Ono et al., 2009), which may contribute to the NMDAR hypofunction thought to occur in the disorder (Olney et al., 1999; Kantrowitz & Javitt, 2010; Marek et al., 2010; Verrall et al., 2010; Coyle, 2012; Labrie et al., 2012). The gene discussed is DAO; the disease is schizophrenia.