Patients with IgAN in severe CKD stages showed higher urinary CXCL1 levels (CKD 3–4: median 26.59 pg/mg, IQR 15.62–50.79 pg/mg vs CKD 1–2: median 16.67 pg/mg, IQR 9.17–29.77 pg/mg, p<0.001). Here, CXCL1 is linked to chronic kidney disease.