UVC (180–280 nm) have been suggested as a prophylactic approach in a mice model of infection against Pseudomonas aeruginosa and Staphylococcus aureus [12] but the function as an APE of this wavelength has not been described. S. aureus is a very common human pathogen susceptible to LL-37 and hBD-1 [6]. This evidence concerns the gene DEFB1 and infection.