In this subgroup, three cases were carrier of the c.798_799delTT mutation [26, 27] and two cases presented the c.211dupA mutation [28]. BRCA1-associated breast cancers are more frequently ductal invasive, high-grade carcinomas, less frequently oestrogen and progesterone receptors positive [23, 24, 26]. This evidence concerns the gene BRCA1 and breast cancer.