F11R and B-cell chronic lymphocytic leukemia: To investigate the potential of reovirus for the treatment of CLL cells, the expression of the reovirus receptor (JAM-1) on CLL cell lines (EHEB and MEC-2) and primary CLL cells from patients was examined; EHEB/MEC-2 cell lines and all primary samples expressed JAM-1 (Figure 1a; n=4).