Statistical analysis showed that the expression of IL-2 increased in the POAG (1.99-fold) and CACG (1.93-fold) groups versus the controls; the difference between the POAG and CACG groups was not significant (POAG vs. controls, P = 0.025; CACG vs. controls, P = 0.035; POAG vs. CACG, P = 0.893). Here, IL2 is linked to open-angle glaucoma.