Interestingly, the potential involvement of kinesins in the pathogenesis of proximal tubular dysfunction has recently been demonstrated in Dent’s disease (another condition presenting with renal Fanconi syndrome) via a direct interaction between ClC-5 chloride-proton exchanger and another kinesin family member kinesin-2 (KIF3B) [38]. This evidence concerns the gene KIF2A and Dent disease.