CD8A and asthma: In the context of asthma, it has been reported that DC-SIGN on human MDDCs mediates cellular responses to, for example, Bermuda grass pollen antigens in vitro leading to the production of TNF-α [11]. Fabp1 (fatty acid binding protein 1, liver) is upregulated +10.5-fold in CD8− DCs from asthmatic-like mice.