In conclusion, chronic alcohol intoxication is accompanied by an increased phosphaturia, ranging sometimes in the values of phosphate diabetes, which is rapidly reversible after alcohol withdrawal, even in the case of long-term consumption, and is inversely correlated with the albuminemia, a slight hyponatremia, an increased CPK level in about 30% of women, and the rapid normalization of the hyperuricemia. This evidence concerns the gene PIK3C2A and Hyponatremia.