ESR1 and Miyoshi myopathy: Sebastien Maillard and other authors,[4] detected the presence of both estrogen receptor alpha and beta in MM cell lines, and showed that both a blockade of cell cycle and an increase of apoptosis were observed in MM cells lines with the use of anti-estrogens drugs, but the exact molecular mechanism of the enhancement of anti-estrogen activity following their incorporation into stealth colloidal formulations is still under current investigation.