To investigate the downstream consequences of iNKT dysfunction during HIV infection of PBMC cytokine/chemokine production, we collected cell culture supernatants from 5 day iNKT αGalCer stimulations and quantified the expression of IFNγ, IL-4, IL-10, IL-13, IL-17, IP-10, MIP-1α, MIP-1β, and TNFα. This evidence concerns the gene IL4 and HIV infectious disease.