Further analysis demonstrated greater correlation between physician-assessed FN risk estimates and subsequent G-CSF orders by certain patient-, physician-, and site-related characteristics, such as colorectal tumors (0.514), planned FOLFOX regimen (0.478), physician with >8–17 years of clinical practice experience (0.451), oncology as primary specialty (0.452), practice treating ≤212 patients per month (first tertile; 0.477), and practice with >4 physicians (0.422; Table S4). The gene discussed is CSF3; the disease is colorectal neoplasm.