CDKN2A and melanoma: Nevus cell senescence may occur, at least in part, because of telomere attrition as the telomere unit has been linked to both high nevus number and melanoma risk.6, 16, 18, 31, 32 Telomere attrition is reported to trigger the induction of tumor suppressor proteins including p16 (INK4a) and many other cell‐cycle genes.10, 11 Age did not impact on SLN status in our study in contrast with the results of Balch et al. 33 but we did not have so many cases in the extreme of ages as seen in the Balch series (such as under 20 years or older than 80 years).