A recent report on African American men (n = 105) with PCa showed higher SPINK1 incidence (23.8%) compared to only ∼8% SPINK1‐positive cases in Caucasian PCa samples (n = 113) 16, highlighting differences at the molecular level in these two clinicopathologically matched PCa cohorts and racial disparities in prostate cancer 35, 36, 37. The gene discussed is SPINK1; the disease is posterior cortical atrophy.