S100A4 and neoplasm: These include the expression of tumour associated markers such as Fibroblast activation protein (FAP) [8], Galectin-3 [9] and S100A4 (FSP-1) [10], evidence of distant spread of pathologically involved cells [11], and activation of pathways implicated in wound healing such as TGFβ mediated myofibroblast differentiation as shown by Kasperkovitz et al [12].