Stimulation of pAKT or pERK was observed in response to growth factors in tumor cells from colorectal (Fig. 4B; n = 48 patients), breast (Fig. 4C; n = 38 patients), NSCLC (Fig. 4D; n = 45 patients), and ovarian (Fig. 4E; n = 37 patients). This evidence concerns the gene EIF2AK3 and non-small cell lung carcinoma.