CD4 and graft versus host disease: The CD4+CD25high lymphocyte count at hematologic recovery was able to discriminate patients at risk for acute (low value) or de novo chronic (high value) GvHD (3.778 ± 0.780 × 106 cells/l vs. 2.042 ± 0.261 × 106 cells/L, p = 0.041, Figure 3).