Recently, oligonol, a lychee fruit-derived low molecular weight polyphenol, was also reported to possess anti-influenza activity through its ability to block the attachment of the virus to MDCK cells, as well as its suppression of the nuclear export of influenza virus ribonucleoprotein (RNP) by blocking ROS-dependent induction of ERK phosphorylation[49]. The gene discussed is RNPC3; the disease is influenza.