Trkb(m) overexpressed in buds in comparison to main tumor body (p < 0.0001) and associated with KRAS mutation. High expression of membranous Trkb-independent adverse prognostic factor. Inverse correlations between expression profile of Trkb(m) and Ki-67 as well as Caspase-3 (53). This evidence concerns the gene KRAS and neoplasm.