PANVAC is a cancer vaccine therapy that contains transgenes for the TAAs MUC-1 and carcinoembryonic antigen (CEA) as well as transgenes for three human T cell costimulatory molecules, collectively known as TRICOM (B7-1, intracellular adhesion molecule-1 and leukocyte function-associated antigen-3) [82]. The gene discussed is CEACAM5; the disease is cancer.