AP-1, NFAT, and NF-κB are important mediators of the expression of cytokines such as CXCL1, CXCL8, and IL-6 in HEK293T cells, monocytes (Schwarz and Murphy, 2001), endothelial cells and KSIMM cells (Pati et al., 2001), which produce an inflammatory environment that promotes transformation of cells and contributes to KS (Cesarman et al., 2000). Here, NFKB1 is linked to Kaposi's sarcoma.