In this study we investigated a range of preoperative blood lipid profiles, TC, HDL, triglyceride (TG), apolipoprotein A1 (apoA1), and apolipoprotein B (apoB), as well as the specific ratio of these markers (TC/HDL, LDL/HDL and apoB/apoA1) of patients with clinically localized PCa who underwent radical prostatectomy (RP), particularly with respect to the relationship between these markers and biochemical recurrence (BCR) after surgery. Here, APOB is linked to posterior cortical atrophy.