Our study showed that after LPS stimulation, UII and UT mRNA expression levels were significantly increased in KCs (all P<0.01 versus control cells), whereas pretreatment using the UT antagonists urantide significantly inhibited LPS-induced UII/UT mRNA expression (all P<0.01 versus LPS-stimulated cells) (Fig. 1). Here, UTS2 is linked to dry eye syndrome.