BRCA2 and ovarian cancer: 2013). It is also likely to be informative in the analysis of the many other susceptible genes related to breast and ovarian cancer that have been discovered (Couch et al. 2014). Indeed, several studies have developed a system for the simultaneous detection of multiple target genes using NGS (Walsh et al. 2010, 2011; Castéra et al. 2014). The identification of mutations in genes other than BRCA1 and BRCA2 will also help understand the genetic heterogeneity and penetrance of HBOC (Walsh et al. 2010; Castéra et al. 2014).