In our study patients with expression values for IL2RA, SORT1, FLT3, and DEFA1 genes above the cutoff values have an increased risk of relapse/death ranging from 3.73 to 27 times compared to B-ALL patients with expression values equal to or below these cutoffs (P values < 0.05). The gene discussed is SORT1; the disease is acute lymphoblastic leukemia.