CTF1 and diastolic heart failure: CT-1 was significantly higher in patients with diastolic heart failure and significantly correlated with NT-proBNP (r = 0.349), with the ratio of early diastolic transmitral flow velocity (E) to early diastolic velocity of mitral annular motion (e′) (r = 0.307), and with the estimated mean PCWP (r = 0.308).