In the context of HIV-1, genetic cohort studies have shown associations of several single nucleotide polymorphisms (SNPs) with different rates of progression and variation in susceptibility to infection [9], which involves genes encoding molecules that participate in the adsorption process and viral penetration into the host cell (CCR5, CCR2, RANTES, and SDF1), in the regulation of the immune response (IL-10, TNFα, and MBL), and in the recognition of epitopes of viral antigens by CD4+ and CD8+ T lymphocytes (human leukocyte antigen or HLA). This evidence concerns the gene IL10 and infection.