Multimedia Appendix 7 lists the genes and their most severe associated ADR. Our analysis highlights previously associated genes and severe ADRs [15], as shown in Table 2. We also highlight three genes predicted by [11] to be associated with neuroleptic malignant syndrome (NMS): HTR2A, NGPR, and COMT. This evidence concerns the gene HTR2A and neuroleptic malignant syndrome.