PBXIP1 and colorectal carcinoma: Moreover, the patients with high expression of HPIP had shorter disease-free survival (DFS) and overall survival (OS) than those with low expression of HPIP (DFS: p = 0.011, OS: p = 0.021) (Fig. 1D, 1E), indicating that HPIP predicts poorer clinical outcome of CRC.