Mice lacking endogenous miR-155 that were fed HFD for 6 months developed increased hepatic steatosis compared to WT controls, accompanied by the significant increase in liver lipid droplets, hepatic TG and TC levels, and serum VLDL/LDL cholesterol levels [10], while in the present study, liver-specific overexpression of miR-155 transgene in Rm155LG/Alb-Cre mice led to decreased hepatic and serum lipid levels, and alleviated HFD-induced fatty liver. Here, ALB is linked to fatty liver disease.